This study is a registry (a collection of information to help study Non-Hodgkin Lymphoma and lymphoproliferative diseases), not a clinical trial. No treatment will be given to any subjects. Patients who agree to take part in this study will have a biopsy to see if they have lymphoma or lymphoproliferative disease. Drawing samples of blood and getting samples of bone marrow are often part of standard of care for patients who may have cancer. When blood is taken for standard tests, you will be asked to give an extra 3 teaspoons of blood for special research studies. If you are not having standard blood work done, you will be asked to provide 3 teaspoons of blood. If a bone marrow sample is being taken for clinical purposes, you will be asked to provide an extra 1-2 teaspoons of bone marrow. No additional bone marrow tests or other invasive tests will be asked of you. Characteristics in the samples of blood may be compared with those in the tissue. Some of the tissue used to make the diagnosis of your disease will be sent to central review centers to confirm that you are eligible to have samples banked on this study. The results will not be given to you or your doctor. Clinical information, such as where the lymphoma occurred in the body or whether you had any other symptoms like fever or pain, will be collected and sent to a central office. Once a year for five years, the study doctor will be asked to update how you are doing at regular check-ups, which will include what type of treatment you were given.
Includes but may not be limited to:
Must be less than 21 years of age
Must have histologically confirmed Non-Hodgkin Lymphoma (except Burkitt/Burkitt-like, diffuse large B-cell, anaplastic large cell, and lymphoblastic lymphomas). All primary Central Nervous System and cutaneous lymphomas of any histology are eligible as are all lymphoproliferative disease
Must not have had chemotherapy or irradiation (to study lesion) within 6 months of surgical excision or biopsy.