Purpose: The purpose of this study is to determine whether the use of the Prontosan Wound Gel (Gel-X) shows a difference in the number of times applied, comfort, and in the healing time of superficial to mid-dermal thickness burns of the face as compared to standard of care cream (antibiotic ointment). Prontosan Wound Gel is an FDA registered gel for wound healing.
The face is a very common body area to get burned. Applying bandages to the face is not as easy as applying bandages to other areas of the body because they may cause claustrophobia (confinement) or do not stay in place. The tip of the nose, the chin and the ears are common areas that end up exposed to air and dry out. Drying out of burn wounds can cause scarring. Moist wounds tend to heal faster than dry wounds. This study will compare two topical treatments (study gel and antibiotic cream).
Participants will be in this research for up to 18 months. Information about the participant’s burn wound will be collected at initial treatment, 2 follow-up visits and one optional final visit that will occur approximately 1 year after the time of wound healing.
If you are eligible and enroll in the study, you will be asked to come to the Inpatient or Outpatient Burn Center (Burn Recovery Center) at the Cedar Crest Campus of Lehigh Valley Hospital. You will then be randomized to receive one of the 2 topical treatments.
Healing of the wounds will be assessed on a regular basis. This will occur in the Inpatient or Outpatient Burn Center until the wound is healed, as is standard of care. Participants will be asked to complete a questionnaire daily that relates to how easy and comfortable the cream or gel is to use. Over time, if it is decided that the wound is healed, the gel or cream will not be used anymore. The questionnaires will only be completed each day until the wound is determined to be healed.
Participants will be asked to return to the Outpatient Burn Center once for an optional final scar evaluation measurement appointment approximately 6-18 months after the burn injury as part of this research study. The scar evaluation measurements are not painful and will be done once.
Eligibility: Inclusion Criteria-including but may not be limited to:
- 2nd degree burns to the face
- 18 years old or older
- Have a facial burn equal to or greater in size than a silver dollar
- Burn injury occurring within 72 hours of study enrollment
Network Office of Research and Innovation