Clinical Trial: Lung Cancer, Cancer

MSK 18-541 Lung study

Full Name

MSK 18-541 Registry Trial of Active Surveillance for Multifocal Ground Glass Opacities (GGOs)

Description

The purpose of this registry study is to actively monitor people with GGOs and collect information about them, so that investigators can learn more about these lesions and about the risk of developing lung cancer in study participants whose GGOs are being monitored in the active surveillance program.

Eligibility

Inclusion Criteria
  • Age greater than 18 years
  • Have two or more GGOs on initial CT imaging
  • GGOs must be measure ≤30 cm and ≥0.6 cm in the greatest dimension
  • GGOs must be greater than half ground glass

    A biopsy is not necessary for inclusion in the trial. Biopsy of a GGO, even with a diagnosis of adenocarcinoma, does not necessarily preclude enrollment in this surveillance protocol. In other words, patients with a diagnosis of adenocarcinoma are still eligible, at the discretion of the clinical and/or investigator, if they meet the above criteria.

    Any GGO that measures <0.6 cm does not need to be followed. At follow-up visits, any new GGO's that meet the eligibility criteria will be captured and followed. Additionally, any pre-existing GGO's that have grown to a size of ≥0.6 cm will be catalogued and followed as well.
Exclusion Criteria
  • Patients who are actively undergoing lung cancer treatment or have a history of such treatment, except for cases of completely resected pathologic stage IA non small cell lung cancer (NSCLC). Patients with stage IA NSCLC and multiple GGOs can enroll in this active surveillance protocol after complete resection of the NSCLC and confirmation of stage on final pathologic assessment.
  • Patients being actively treated for other malignancies (not including lung cancer) or who have previously been treated for other malignancies and have been cancer-free for <3 years before study registration, other than non-melanoma skin cancer, superficial bladder cancer, or CIS of the cervix.
    The presence of any solid lesion ≥0.6 cm on initial chest CT scan imaging
Doctor(s) Running This Study

Accepting New Patients

Specialties
Pulmonology
Sleep Medicine
Area of focus
Pulmonary
Sleep Medicine
Critical Care
Locations

1250 S Cedar Crest Blvd
Suite 205
Allentown, PA 18103-6271
United States

17th & Chew Sts
PO Box 7017
Allentown, PA 18105-7017
United States

2101 Emrick Blvd
Suite 200
Bethlehem, PA 18020-8040
United States