Mark C. Knouse, MD headshot

Mark C. Knouse, MD

Chief, Division of Infectious Diseases

Infectious Diseases

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Monday - Friday: 7 a.m. – 8 p.m.
Saturday: 9 a.m. – 5 p.m.

Accepting New Patients

Lehigh Valley Physician Group

Infectious Diseases
Conditions treated
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Services offered
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Area of focus ?
Infectious Disease, Travel Medicine
Languages spoken
English, Spanish (some)

Dr. Knouse's Locations

Conditions Dr. Knouse Treats

  • Cellulitis
  • HIV and AIDS
  • Hepatitis
  • Infections
  • Infectious Conditions
  • Leukocytosis
  • Lyme Disease
  • Major Infections
  • Meningitis
  • Minor Infections
  • Nontuberculous Mycobacteria
  • Osteomyelitis (Bone Infection)
  • Pneumonia
  • Sexually Transmitted Diseases (STDs)
  • Shingles
  • Skin Infections
  • Tuberculosis

Services Dr. Knouse Offers

About Dr. Knouse

Philosophy of care

My general philosophy of medicine and treating patients is that I believe every patient requires the same level of excellent care. We always give 110 percent effort to each patient care problem. Our goal is to try to make a rapid diagnosis and institute an extremely effective treatment plan. In this regard we need to be committed fully to each patient every day, all the time so that we may provide the best level of service to our patients here at Lehigh Valley Health Network.We believe that each patient should be treated with the best scientific technology, but also with as much compassion as possible, thus combining the best of science and the art of medicine.

Why I entered medicine

I had several relatives who were physicians. They were great role models for me in my younger years. I always looked up to them as well-regarded professionals in their field. They were extremely well-regarded within our family as well. They were very compassionate people who went out of their way to help others. They were very successful in their scientific careers. This greatly influenced my decision to enter the field of medicine. I chose the field of infectious diseases because our cases are always fascinating and at times quite difficult. Diagnosis often requires a significant amount of investigation, often "sleuthing" in a detective-style fashion that I find extremely exciting. In our field there are always new diseases, such as the recent SARS epidemic, Avian influenza and many others that require immediate action. This keeps the level of scientific interest quite high and makes the job very challenging, and I enjoy that.

Personal interests

At the present time I have very little spare time. The free time I do have I enjoy with my family, often at sporting events or other family outings. I do enjoy photography as a hobby and hopefully will be able to devote more time to that in the near future.


Dickinson College, BS- Bachelor of Science, 1978

Medical Training
Georgetown University School of Medicine, MD - Doctor of Medicine, 1982


Residency 1983
Internal Medicine, Allentown Affiliated Hospitals, Allentown, PA

Residency 1984
Internal Medicine, Allentown Affiliated Hospitals, Allentown, PA

Residency 1985
Internal Medicine, Allentown Affiliated Hospitals, Allentown, PA

Fellowship 1988
Infectious Disease, Temple University Hospital, Philadelphia, PA

Fellowship 1989
Infectious Disease, Temple University Hospital, Philadelphia, PA


American Board of Internal Medicine - Internal Medicine
American Board of Internal Medicine - Infectious Disease

Ratings and Reviews

About Our Ratings and Reviews

About our Survey

Our physicians and advanced practice clinicians (CRNPs and PA-Cs) are among the nation's best. That's why we show you patient satisfaction ratings and comments so you can read about and get to know our providers through the eyes of their patients.

To ensure our ratings and comments come only from verified patients, we work with NRC Health, a third-party organization. NRC Health sends patient satisfaction surveys on LVPG's behalf following an office visit or procedure. They ask patients about their impression of the health care provider and the doctor's or advanced practice clinician's communication skills.

What is included in the star rating?

Star ratings are based on a scale of 1-5 stars, 5 being the best. The rating includes responses to these provider-related questions:

  1. Physician Communication Questions
    1. Did this provider give you enough information about your health and treatment?
    2. Did this provider give you easy to understand information about your health questions and concerns?
    3. Did this provider listen carefully to you?
    4. Did this provider seem to know your medical history?
    5. Did you trust this provider with your care?
  2. Overall Provider Rating Question
    1. Using any number from 0 to 10, where 0 is the worst provider possible and 10 is the best provider possible, what number would you use to rate this provider?

Why don't all doctors or advanced practice clinicians have a rating?

In order to have enough data to measure and compare, a health care provider must have at least 30 completed patient satisfaction surveys. Surveys are included for a period of 12 months from submission.