Marie S. O'Brien, DO headshot

Marie S. O'Brien, DO


Need help scheduling?
Call 888-402-LVHN (5846)

Monday - Friday: 7 a.m. – 8 p.m.
Saturday: 9 a.m. – 5 p.m.

Accepting New Patients

Lehigh Valley Physician Group

Conditions treated
View Full List
Services offered
View Full List
Area of focus ?
Languages spoken

Conditions Dr. O'Brien Treats

  • Ankylosing Spondylitis
  • Antiphospholipid Syndrome (APS)
  • Arthritis
  • Autoimmune Diseases
  • Dermatomyositis
  • Gout
  • Knee Pain
  • Lupus
  • Myopathies
  • Osteoarthritis
  • Osteoarthritis of Knee
  • Osteopenia (Bone Loss)
  • Osteoporosis
  • Polymyalgia Rheumatica (PMR)
  • Polymyositis
  • Pseudogout
  • Psoriatic Arthritis
  • Raynaud's Disease
  • Rheumatoid Arthritis
  • Sarcoidosis
  • Sjögren's Syndrome
  • Systemic Sclerosis/Scleroderma
  • Vasculitis/Wegener's

Services Dr. O'Brien Offers

  • Arthrocentesis (Joint Aspiration)
  • Rheumatology

About Dr. O'Brien

Philosophy of care

Patients with chronic diseases need special care and attention. It's important for me to educate patients so they feel more in control of their disease and their lives.

Why I entered medicine

Rheumatology is a very challenging specialty for physicians as well as for patients. The diseases are complex and encompass every field of medicine. Growing up in my community I was always grateful for the care given to me and my family. As a result, I wanted to provide my community medical care they needed, particularly those with challenging rheumatic illnesses.

Community involvement

Growing up in the Lehigh Valley, I enjoy participating in events with the Arthritis Foundation and running local races with my father.

Personal interests

Spending time with my family and friends. I also enjoy running outdoors and exercise when time allows.


Cedar Crest College, BS - Biology, 1998

Medical Training
Philadelphia College of Osteopathic Medicine, DO - Doctor of Osteopathy, 2002


Internship 2003
Lehigh Valley Health Network, Allentown, PA

Residency 2004
Internal Medicine, Lehigh Valley Health Network, Allentown, PA

Residency 2005
Internal Medicine, Lehigh Valley Health Network, Allentown, PA

Fellowship 2006
Rheumatology, Thomas Jefferson University Hospital, Philadelphia, PA

Fellowship 2007
Rheumatology, Thomas Jefferson University Hospital, Philadelphia, PA


American Board of Internal Medicine - Internal Medicine
American Board of Internal Medicine - Rheumatology

Ratings and Reviews

About Our Ratings and Reviews

About our Survey

Our physicians and advanced practice clinicians (CRNPs and PA-Cs) are among the nation's best. That's why we show you patient satisfaction ratings and comments so you can read about and get to know our providers through the eyes of their patients.

To ensure our ratings and comments come only from verified patients, we work with NRC Health, a third-party organization. NRC Health sends patient satisfaction surveys on LVPG's behalf following an office visit or procedure. They ask patients about their impression of the health care provider and the doctor's or advanced practice clinician's communication skills.

What is included in the star rating?

Star ratings are based on a scale of 1-5 stars, 5 being the best. The rating includes responses to these provider-related questions:

  1. Physician Communication Questions
    1. Did this provider give you enough information about your health and treatment?
    2. Did this provider give you easy to understand information about your health questions and concerns?
    3. Did this provider listen carefully to you?
    4. Did this provider seem to know your medical history?
    5. Did you trust this provider with your care?
  2. Overall Provider Rating Question
    1. Using any number from 0 to 10, where 0 is the worst provider possible and 10 is the best provider possible, what number would you use to rate this provider?

Why don't all doctors or advanced practice clinicians have a rating?

In order to have enough data to measure and compare, a health care provider must have at least 30 completed patient satisfaction surveys. Surveys are included for a period of 12 months from submission.