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Find a Clinical Trial

Search for innovative treatments that are not currently available to all patients.

Common Searches: Clinical Trials

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  • (-) Lehigh Valley Hospital–Hazleton
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Type of Trial

  • Cancer (38)

Diagnosis or Condition

Patient Type

  • Adult (38)

Phase

  • Phase II (11)
  • Phase III (21)

Location

38 Clinical Trial found
  • (-) Lehigh Valley Hospital–Hazleton
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A012103 Breast Cancer

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Clinical Trial

Breast Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG S2013 Observational Study

IMMUNE CHECKPOINT INHIBITOR TOXICITY (I-CHECKIT):  A PROSPECTIVE OBSERVATIONAL STUDY

Clinical Trial

Cancer

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

URCC-21038 Observational

A Prospective Cohort Study of Cancer Survivors Treated with anti-PD-1/anti-PD-L1 Immunotherapy in a Community Oncology Setting

Clinical Trial

Cancer

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

A151804 Immunotherapy

A151804 Establishment of a National Biorepository to Advance Studies of Immune-Related Adverse Events

Clinical Trial

Cancer

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

NRG-BR009 Breast Cancer

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25 (OFSET)

Clinical Trial

Breast Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG S2206 Breast Cancer

Phase III Trial Of Neoadjuvant Durvalumab (NSC 778709) Plus Chemotherapy Versus Chemotherapy Alone For Adults With MammaPrint High 2 Risk (MP2) Hormone Receptor (HR) Positive / Human Epidermal Growth Factor Receptor (HER2) Negative Stage II-III Breast Cancer

Clinical Trial

Breast Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG S2303 Esophageal Adenocarcinoma

Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab versus Paclitaxel + Ramucirumab in Patients with PD-L1 CPS ≥ 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE).

Clinical Trial

Cancer, Esophageal Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

EA5231 Lung Cancer

A Randomized Phase III Trial of Checkpoint blockade in Lung cancEr patients in the Adjuvant setting based on pathologic Response following neoadjuvant therapy (CLEAR)

Clinical Trial

Cancer, Lung Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG S2414 Lung Cancer

A RANDOMIZED PHASE III TRIAL INCORPORATING PATHOLOGIC COMPLETE RESPONSE IN PARTICIPANTS WITH EARLY STAGE NON SMALL CELL LUNG CANCER TO OPTIMIZE IMMUNOTHERAPY IN THE ADJUVANT SETTING (INSIGHT)

Clinical Trial

Cancer, Lung Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG S2312 Prostate Cancer

A Phase III Study of Cabazitaxel with or without Carboplatin in Patients with Metastatic Castrate Resistant Prostate Cancer (MCRPC), Stratified by Aggressive Variant Signature

Clinical Trial

Prostate Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG S1931 Renal Cancer

Phase III Trial of Immunotherapy-Based Combination Therapy with or Without Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma (Probe Trial)

Clinical Trial

Cancer, Kidney Cancer (Renal Cancer)

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

MyeloMATCH MM1YA-CTG01

A MEASURABLE RESIDUAL DISEASE (MRD) FOCUSED, PHASE II STUDY OF VENETOCLAX PLUS CHEMOTHERAPY FOR NEWLY DIAGNOSED YOUNGER PATIENTS WITH INTERMEDIATE RISK ACUTE MYELOID LEUKEMIA: A TIER 1 MYELOMATCH CLINICAL TRIAL

Clinical Trial

Acute Myeloid Leukemia, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

MyeloMATCH MM1YA-S01

A RANDOMIZED PHASE II STUDY COMPARING CYTARABINE + DAUNORUBICIN (7+3) VS (DAUNORUBICIN AND CYTARABINE) LIPOSOME, CYTARABINE + DAUNORUBICIN + VENETOCLAX, AZACITIDINE + VENETOCLAX, AND (DAUNORUBICIN AND CYTARABINE) LIPOSOME + VENETOCLAX IN PATIENTS AGED 59 OR YOUNGER WHO ARE CONSIDERED HIGH-RISK (ADVERSE) ACUTE MYELOID LEUKEMIA AS DETERMINED BY MYELOMATCH; A MYELOMATCH CLINICAL TRIAL

Clinical Trial

Acute Myeloid Leukemia, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

MyeloMATCH MM1OA-EA02

A Randomized Phase II Study of Venetoclax and HMA-based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed FLT3-mutated Acute Myeloid Leukemia (AML): A MyeloMATCH Treatment Trial

Clinical Trial

Acute Myeloid Leukemia, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

MyeloMATCH MASTER SCREENING AND REASSESSMENT PROTOCOL

MyeloMATCH MASTER SCREENING AND REASSESSMENT PROTOCOL (MSRP) FOR TIER ADVANCEMENT IN THE NCI MYELOMATCH CLINICAL TRIALS

Clinical Trial

Acute Myeloid Leukemia, Cancer

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

A092205 Head and Neck Cancers

Randomized Phase III Trial of Pembrolizumab vs. Pembrolizumab/Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma with Platinum Refractory Disease

Clinical Trial

Cancer, Head and Neck Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG-S1501

PROSPECTIVE OBSERVATIONAL COHORT STUDY OF PATIENTS WITH METASTATIC HER-2+ BREAST CANCER AT RISK OF CARDIAC TOXICITY

Clinical Trial

Breast Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

A032201 Renal Cell Carcinoma

SHORT TERM INTENSIFIED PEMBROLIZUMAB (KEYTRUDA) AND TIVOZANIB FOR HIGH-RISK RENAL CELL CARCINOMA - STRIKE

Clinical Trial

Cancer, Kidney Cancer (Renal Cancer)

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

EAA181 Multiple Myeloma

Effective Quadruplet Utilization After Treatment Evaluation (EQUATE): A Randomized Phase III Trial for Newly Diagnosed Multiple Myeloma Not Intended for Early Autologous Transplantation

Clinical Trial

Cancer, Multiple Myeloma

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

S1802 Prostate Cancer

Phase III Randomized Trial of Standard Systemic Therapy (SST) Versus Standard Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor in Metastatic Prostate Cancer).

Clinical Trial

Prostate Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

NRG-GY026 Gynecological Cancer

A PHASE II/III STUDY OF PACLITAXEL/CARBOPLATIN ALONE OR COMBINED WITH EITHER TRASTUZUMAB AND HYALURONIDASE-OYSK (HERCEPTIN HYLECTA) OR PERTUZUMAB, TRASTUZUMAB, AND HYALURONIDASE-ZZXF (PHESGO) IN HER2 POSITIVE, STAGE I-IV ENDOMETRIAL SEROUS CARCINOMA OR CARCINOSARCOMA

Clinical Trial

Gynecologic Cancer, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

WF2304-A172401 Multi-Site Cancer

Complementary Options for Symptom Management In Cancer (COSMIC): Assessing Benefits and Harms of Cannabis and Cannabinoid Use Among a Cohort of Cancer Patients Treated in Community Oncology Clinics

Clinical Trial

Cancer

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

Alliance A031701

ALLIANCE A031701: A PHASE II STUDY OF DOSE-DENSE GEMCITABINE PLUS CISPLATIN (DDGC) IN PATIENTS WITH MUSCLE-INVASIVE BLADDER CANCER WITH BLADDER PRESERVATION FOR THOSE PATIENTS WHOSE TUMORS HARBOR DELETERIOUS DNA DAMAGE RESPONSE (DDR) GENE ALTERATIONS

Clinical Trial

Bladder Cancer, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

S1501

Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III

Clinical Trial

Breast Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Ranju Gupta, MD
Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

LungMAP

A Master Protocol to Evaluate Biomarker-Driven Therapies and Immunotherapies in Previously-Treated Non-Small Cell Lung Cancer (Lung-MAP Screening Study)

Clinical Trial

Lung Cancer, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

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