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Find a Clinical Trial

Search for innovative treatments that are not currently available to all patients.

Common Searches: Clinical Trials

  • Cancer
  • Pediatrics

Filter Results   information

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Type of Trial

  • Cancer (66)
  • Non-Cancer (18)

Diagnosis or Condition

Patient Type

  • Adult (79)
  • Pediatric (5)

Phase

  • Phase I (6)
  • Phase II (19)
  • Phase III (38)
  • Phase IV (2)

Location

85 Clinical Trial found

A092205 Head and Neck Cancers

Randomized Phase III Trial of Pembrolizumab vs. Pembrolizumab/Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma with Platinum Refractory Disease

Clinical Trial

Cancer, Head and Neck Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

WF2304-A172401 Multi-Site Cancer

Complementary Options for Symptom Management In Cancer (COSMIC): Assessing Benefits and Harms of Cannabis and Cannabinoid Use Among a Cohort of Cancer Patients Treated in Community Oncology Clinics

Clinical Trial

Cancer

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

IOV-EAP-OO4 Melanoma

Expanded Access Program of AMTAGVI that is Out of Specification for Commercial Release

Clinical Trial

Cancer, Melanoma

Phase

Phase
1

Doctor(s) Running This Study

Suresh G. Nair, MD
Location:
Lehigh Valley Hospital–Cedar Crest

BMS CA244-0008 IZABRIGHT Breast Cancer

A Randomized, Open-label, Inferentially Seamless Phase 2/3 Study of Izalontamab Brengitecan (BMS-986507) versus Treatment of Physician’s Choice in Patients with Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer (TNBC) or ER-low, HER2-negative BC who are Ineligible for Anti-PD1/PD-L1 Treatment

Clinical Trial

Breast Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Nicholas E. Lamparella, DO
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg

APEC14B1 Younger Patients with Cancer study (PRO00003477)

The Project Every Child Protocol: A Registry, Eligibility, Screening, Biology and Outcome Study

Clinical Trial

Pediatric Cancer

Location:
Lehigh Valley Hospital–Cedar Crest

AGS-003 immunotherapy for kidney cancer

Kidney Cancer (ARGOS AGS-003-007): An international phase 3, randomized trial of Autologous Dendritic cell immunotherapy (AGS-003) Plus standard Treatment of advanced renal cell carcinoma (ADAPT) (2_PRO00000324)

Clinical Trial

Cancer

Doctor(s) Running This Study

Suresh G. Nair, MD

ALTEO5N1: Long-Term Follow-up protocol (PRO00001591)

ALTEO5N1: UMBRELLA LONG-TERM FOLLOW-UP PROTOCOL

 

Clinical Trial

Cancer

JNJ KLK2-PASenger Prostate Cancer

A Phase 3 Randomized, Open-label Study of Pasritamig (JNJ-78278343), a T-cell-redirecting Agent Targeting Human Kallikrein 2, With Docetaxel Versus Docetaxel for Metastatic Castration-resistant Prostate Cancer

Clinical Trial

Prostate Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Paul Palyca, MD
Location:
Lehigh Valley Hospital–Cedar Crest

BMS CA 266-0003

A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination with Chemotherapy Versus Bevacizumab in Combination with Chemotherapy in Participants with Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Clinical Trial

Cancer, Colorectal Cancer (Colon Cancer and Rectal Cancer)

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg

KO-MEN-008

KO-MEN-008 A Study to Investigate the Safety and Tolerability of Ziftomenib Combinations in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Clinical Trial

Acute Myeloid Leukemia, Lung Cancer, Cancer

Phase

Phase
1

Doctor(s) Running This Study

Don J. Park, MD, PhD
Location:
Lehigh Valley Hospital–Cedar Crest

Left vs. Left

Cardiac Resynchronization Therapy Using His/Left Bundle Branch Pacing vs Biventricular Pacing with a Left Ventricular Epicardial Lead in Patients with Heart Failure (HF) with Left Ventricular Ejection Fraction (LVEF) ≤ 50% and with either a Wide QRS Complex (> 130 ms) or with/anticipated > 40% Pacing Randomized Clinical Trial (RCT) (Left vs Left RCT) Protocol Number NCT05650658

Clinical Trial

Heart and Vascular

Doctor(s) Running This Study

Babak Bozorgnia, MD
Location:
Lehigh Valley Hospital–Cedar Crest

GENEPHIT: Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects with Non-Ischemic NYHA Class III Heart Failure

A Phase 2, Adaptive, Double-blinded, Placebo Controlled, Randomized, Multi-center Trial to Evaluate the Efficacy, Safety and Tolerability of Intracoronary Infusion of AB-1002 in Adult Subjects With New York Heart Association (NYHA) Class III Heart Failure and Non-ischemic Cardiomyopathy

Clinical Trial

Heart and Vascular

Phase

Phase
2
Location:
Lehigh Valley Hospital–Cedar Crest

A Phase 3 Study of Nipocalimab in Pregnancies at Risk for Sever HDFN (AZALEA Study)

A Phase 3 Randomized, Placebo-Controlled, Double-blind, Multicenter Study to Evaluate the Efficacy and Safety of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (*HDFN)

Clinical Trial

Obstetrics and Gynecology

Phase

Phase
3

Doctor(s) Running This Study

Meredith L. Rochon, MD
Location:
Lehigh Valley Hospital–Cedar Crest

SWOG S2312 Prostate Cancer

A Phase III Study of Cabazitaxel with or without Carboplatin in Patients with Metastatic Castrate Resistant Prostate Cancer (MCRPC), Stratified by Aggressive Variant Signature

Clinical Trial

Prostate Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

BMS CA057-001

A PHASE 3, TWO-STAGE, RANDOMIZED, MULTICENTER, OPEN-LABEL STUDY COMPARING MEZIGDOMIDE (CC-92480), BORTEZOMIB AND DEXAMETHASONE (MEZIVd) VERSUS POMALIDOMIDE, BORTEZOMIB AND DEXAMETHASONE (PVd) IN SUBJECTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA (RRMM): SUCCESSOR-1

Clinical Trial

Cancer, Multiple Myeloma

Phase

Phase
3
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg

LYL314-101 Lymphoma

A PHASE 1/2 MULTI-CENTER STUDY EVALUATING THE SAFETY AND EFFICACY OF LYL314, A CD19/CD20 DUAL-TARGETING CHIMERIC ANTIGEN RECEPTOR T-CELL THERAPY IN PARTICIPANTS WITH AGGRESSIVE B-CELL NON-HODGKIN LYMPHOMA

Clinical Trial

Non-Hodgkin Lymphoma, Cancer

Phase

Phase
1

Doctor(s) Running This Study

Usama Gergis, MD, MBA
Location:
Lehigh Valley Hospital–Cedar Crest

NRG-CC014

RADIATION THERAPY FOR HIGH-RISK ASYMPTOMATIC BONE METASTASES: A PRAGMATIC MULTICENTER RANDOMIZED PHASE 3 CLINICAL TRIAL (PREEMPT)

Clinical Trial

Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

EMN30 Multiple Myeloma

Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation” (MajesTEC-4)

Clinical Trial

Cancer, Multiple Myeloma

Phase

Phase
3

Doctor(s) Running This Study

Bradley W. Lash, MD
Location:
Lehigh Valley Hospital–Cedar Crest

RTOG 1216, Head and Neck Cancer

Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck

Clinical Trial

Cancer, Head and Neck Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

EA5231 Lung Cancer

A Randomized Phase III Trial of Checkpoint blockade in Lung cancEr patients in the Adjuvant setting based on pathologic Response following neoadjuvant therapy (CLEAR)

Clinical Trial

Cancer, Lung Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG S2414 Lung Cancer

A RANDOMIZED PHASE III TRIAL INCORPORATING PATHOLOGIC COMPLETE RESPONSE IN PARTICIPANTS WITH EARLY STAGE NON SMALL CELL LUNG CANCER TO OPTIMIZE IMMUNOTHERAPY IN THE ADJUVANT SETTING (INSIGHT)

Clinical Trial

Cancer, Lung Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

GORE® EXCLUDER® TAMBE PAS

GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis Post-Approval Study

Clinical Trial

Heart and Vascular, Surgery

Doctor(s) Running This Study

Benjamin M. Jackson, MD, MS
Location:
Lehigh Valley Hospital–Cedar Crest

C – Beyond AT-01B-007

Phase 3, Randomized, Controlled, Open-label Study to Compare the Efficacy and Safety of Bemnifosbuvir-Ruzasvir Fixed-dose Combination (BEM/RZR FDC) Versus Sofosbuvir-Velpatasvir Fixed-dose Combination (SOF/VEL FDC) in Subjects with Chronic Hepatitis C Virus (HCV) Infection

Phase

Phase
3

Doctor(s) Running This Study

Orlando J. Penaloza, MD
Location:
Lehigh Valley Hospital–17th Street
Lehigh Valley Hospital–Cedar Crest

ENABLE

REal world experieNce with BRIUMVI® (ublituximAB-xiiy)  treated patients:  a Longitudinal rEgistry study (ENABLE)

Clinical Trial

Neurology

Phase

Phase
4

Doctor(s) Running This Study

Gary W. Clauser, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg

RESTORE

RESTORE Study (REdo tranScatheter aortic valve replacement for Transcatheter aOrtic valve failuRE)

Clinical Trial

Heart and Vascular, Surgery

Doctor(s) Running This Study

Dzanan Ramic, MD
Location:
Lehigh Valley Hospital–Cedar Crest

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Lehigh Valley Health Network, part of Jefferson Health, holds itself accountable, at every level of the organization, to nurture an environment of inclusion and respect, by valuing the uniqueness of every individual, celebrating and reflecting the rich diversity of its communities, and taking meaningful action to cultivate an environment of fairness, belonging & opportunity.