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Find a Clinical Trial

Search for innovative treatments that are not currently available to all patients.

Common Searches: Clinical Trials

  • Cancer
  • Pediatrics

Filter Results  

Type of Trial

  • Cancer (60)
  • Non-Cancer (18)

Diagnosis or Condition

Patient Type

  • Adult (74)
  • Pediatric (4)

Phase

  • Phase I (3)
  • Phase II (18)
  • Phase III (36)
  • Phase IV (2)

Location

79 Clinical Trial found

GENEPHIT: Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects with Non-Ischemic NYHA Class III Heart Failure

A Phase 2, Adaptive, Double-blinded, Placebo Controlled, Randomized, Multi-center Trial to Evaluate the Efficacy, Safety and Tolerability of Intracoronary Infusion of AB-1002 in Adult Subjects With New York Heart Association (NYHA) Class III Heart Failure and Non-ischemic Cardiomyopathy

Clinical Trial

Heart and Vascular

Phase

Phase
2
Location:
Lehigh Valley Hospital–Cedar Crest

BMS CA057-001

A PHASE 3, TWO-STAGE, RANDOMIZED, MULTICENTER, OPEN-LABEL STUDY COMPARING MEZIGDOMIDE (CC-92480), BORTEZOMIB AND DEXAMETHASONE (MEZIVd) VERSUS POMALIDOMIDE, BORTEZOMIB AND DEXAMETHASONE (PVd) IN SUBJECTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA (RRMM): SUCCESSOR-1

Clinical Trial

Cancer, Multiple Myeloma

Phase

Phase
3
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg

Left vs. Left

Cardiac Resynchronization Therapy Using His/Left Bundle Branch Pacing vs Biventricular Pacing with a Left Ventricular Epicardial Lead in Patients with Heart Failure (HF) with Left Ventricular Ejection Fraction (LVEF) ≤ 50% and with either a Wide QRS Complex (> 130 ms) or with/anticipated > 40% Pacing Randomized Clinical Trial (RCT) (Left vs Left RCT) Protocol Number NCT05650658

Clinical Trial

Heart and Vascular

Doctor(s) Running This Study

Babak Bozorgnia, MD
Location:
Lehigh Valley Hospital–Cedar Crest

KO-MEN-008

KO-MEN-008 A Study to Investigate the Safety and Tolerability of Ziftomenib Combinations in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Clinical Trial

Acute Myeloid Leukemia, Lung Cancer, Cancer

Phase

Phase
1

Doctor(s) Running This Study

Don J. Park, MD, PhD
Location:
Lehigh Valley Hospital–Cedar Crest

SWOG S2312 Prostate Cancer

A Phase III Study of Cabazitaxel with or without Carboplatin in Patients with Metastatic Castrate Resistant Prostate Cancer (MCRPC), Stratified by Aggressive Variant Signature

Clinical Trial

Prostate Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG S1931 Renal Cancer

Phase III Trial of Immunotherapy-Based Combination Therapy with or Without Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma (Probe Trial)

Clinical Trial

Cancer, Kidney Cancer (Renal Cancer)

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

MyeloMATCH MM1YA-CTG01

A MEASURABLE RESIDUAL DISEASE (MRD) FOCUSED, PHASE II STUDY OF VENETOCLAX PLUS CHEMOTHERAPY FOR NEWLY DIAGNOSED YOUNGER PATIENTS WITH INTERMEDIATE RISK ACUTE MYELOID LEUKEMIA: A TIER 1 MYELOMATCH CLINICAL TRIAL

Clinical Trial

Acute Myeloid Leukemia, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

MyeloMATCH MM1YA-S01

A RANDOMIZED PHASE II STUDY COMPARING CYTARABINE + DAUNORUBICIN (7+3) VS (DAUNORUBICIN AND CYTARABINE) LIPOSOME, CYTARABINE + DAUNORUBICIN + VENETOCLAX, AZACITIDINE + VENETOCLAX, AND (DAUNORUBICIN AND CYTARABINE) LIPOSOME + VENETOCLAX IN PATIENTS AGED 59 OR YOUNGER WHO ARE CONSIDERED HIGH-RISK (ADVERSE) ACUTE MYELOID LEUKEMIA AS DETERMINED BY MYELOMATCH; A MYELOMATCH CLINICAL TRIAL

Clinical Trial

Acute Myeloid Leukemia, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

MyeloMATCH MM1OA-EA02

A Randomized Phase II Study of Venetoclax and HMA-based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed FLT3-mutated Acute Myeloid Leukemia (AML): A MyeloMATCH Treatment Trial

Clinical Trial

Acute Myeloid Leukemia, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

MyeloMATCH MASTER SCREENING AND REASSESSMENT PROTOCOL

MyeloMATCH MASTER SCREENING AND REASSESSMENT PROTOCOL (MSRP) FOR TIER ADVANCEMENT IN THE NCI MYELOMATCH CLINICAL TRIALS

Clinical Trial

Acute Myeloid Leukemia, Cancer

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

A092205 Head and Neck Cancers

Randomized Phase III Trial of Pembrolizumab vs. Pembrolizumab/Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma with Platinum Refractory Disease

Clinical Trial

Cancer, Head and Neck Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG-S1501

PROSPECTIVE OBSERVATIONAL COHORT STUDY OF PATIENTS WITH METASTATIC HER-2+ BREAST CANCER AT RISK OF CARDIAC TOXICITY

Clinical Trial

Breast Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

A032201 Renal Cell Carcinoma

SHORT TERM INTENSIFIED PEMBROLIZUMAB (KEYTRUDA) AND TIVOZANIB FOR HIGH-RISK RENAL CELL CARCINOMA - STRIKE

Clinical Trial

Cancer, Kidney Cancer (Renal Cancer)

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

EAA181 Multiple Myeloma

Effective Quadruplet Utilization After Treatment Evaluation (EQUATE): A Randomized Phase III Trial for Newly Diagnosed Multiple Myeloma Not Intended for Early Autologous Transplantation

Clinical Trial

Cancer, Multiple Myeloma

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

S1802 Prostate Cancer

Phase III Randomized Trial of Standard Systemic Therapy (SST) Versus Standard Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor in Metastatic Prostate Cancer).

Clinical Trial

Prostate Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

NRG-GY026 Gynecological Cancer

A PHASE II/III STUDY OF PACLITAXEL/CARBOPLATIN ALONE OR COMBINED WITH EITHER TRASTUZUMAB AND HYALURONIDASE-OYSK (HERCEPTIN HYLECTA) OR PERTUZUMAB, TRASTUZUMAB, AND HYALURONIDASE-ZZXF (PHESGO) IN HER2 POSITIVE, STAGE I-IV ENDOMETRIAL SEROUS CARCINOMA OR CARCINOSARCOMA

Clinical Trial

Gynecologic Cancer, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

WF2304-A172401 Multi-Site Cancer

Complementary Options for Symptom Management In Cancer (COSMIC): Assessing Benefits and Harms of Cannabis and Cannabinoid Use Among a Cohort of Cancer Patients Treated in Community Oncology Clinics

Clinical Trial

Cancer

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

Aptis PRUJ IDE

A prospective, multi center, single Arm clinical trial of the safety and effectiveness of the Aptis Proximal Radial Ulnar Joint Prosthesis for the treatment of patients with Proximal Radioulnar joint disorders.

Clinical Trial

Surgery

Doctor(s) Running This Study

Paul A. Sibley, DO
Location:
Lehigh Valley Hospital–Cedar Crest

BMS CA234-0001 MalignantTumor

BMS CA234-0001 A Phase 1/1b Open-label Study of BMS-986488 as Monotherapy and Combination Therapy in Participants with Advanced Malignant Tumors

Clinical Trial

Cancer

Phase

Phase
1

Doctor(s) Running This Study

Suresh G. Nair, MD
Location:
Lehigh Valley Hospital–Cedar Crest

NRG-GY037 Cervical Cancer

A Phase III Study of Induction Pembrolizumab and Chemotherapy Followed by Chemoradiation and Pembrolizumab vs Chemoradiation and Pembrolizumab Both Followed by Pembrolizumab for High Risk Locally Advanced Cervical Cancer

Clinical Trial

Cancer, Cervical Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

GORE® EXCLUDER® TAMBE PAS

GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis Post-Approval Study

Clinical Trial

Heart and Vascular, Surgery

Doctor(s) Running This Study

Benjamin M. Jackson, MD, MS
Location:
Lehigh Valley Hospital–Cedar Crest

AGS-003 immunotherapy for kidney cancer

Kidney Cancer (ARGOS AGS-003-007): An international phase 3, randomized trial of Autologous Dendritic cell immunotherapy (AGS-003) Plus standard Treatment of advanced renal cell carcinoma (ADAPT) (2_PRO00000324)

Clinical Trial

Cancer

Doctor(s) Running This Study

Suresh G. Nair, MD

ALTEO5N1: Long-Term Follow-up protocol (PRO00001591)

ALTEO5N1: UMBRELLA LONG-TERM FOLLOW-UP PROTOCOL

 

Clinical Trial

Cancer

APEC14B1 Younger Patients with Cancer study (PRO00003477)

The Project Every Child Protocol: A Registry, Eligibility, Screening, Biology and Outcome Study

Clinical Trial

Pediatric Cancer

Location:
Lehigh Valley Hospital–Cedar Crest

C – Beyond AT-01B-007

Phase 3, Randomized, Controlled, Open-label Study to Compare the Efficacy and Safety of Bemnifosbuvir-Ruzasvir Fixed-dose Combination (BEM/RZR FDC) Versus Sofosbuvir-Velpatasvir Fixed-dose Combination (SOF/VEL FDC) in Subjects with Chronic Hepatitis C Virus (HCV) Infection

Phase

Phase
3

Doctor(s) Running This Study

Orlando J. Penaloza, MD
Location:
Lehigh Valley Hospital–17th Street
Lehigh Valley Hospital–Cedar Crest

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