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Find a Clinical Trial

Search for innovative treatments that are not currently available to all patients.

Common Searches: Clinical Trials

  • Cancer
  • Pediatrics

Filter Results   information

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Type of Trial

  • Cancer (66)
  • Non-Cancer (18)

Diagnosis or Condition

Patient Type

  • Adult (79)
  • Pediatric (5)

Phase

  • Phase I (6)
  • Phase II (19)
  • Phase III (38)
  • Phase IV (2)

Location

85 Clinical Trial found

Dal-GenE-2

A phase III, double-blind, randomized placebo-controlled study to evaluate the effects of dalcetrapib on cardiovascular (CV) risk in a genetically defined population with recent Acute Coronary Syndrome (ACS): The DAL-302 (dal-GenE-2) trial

Clinical Trial

Heart and Vascular

Phase

Phase
3

Doctor(s) Running This Study

Eric E. Elgin, MD
Location:
Lehigh Valley Hospital–Cedar Crest

Prevail Global

A randomized controlled study of the Prevail Drug-Coated Balloon in subjects with in-stent restenosis and a single arm prospectively enrolled study of the Prevail Drug-Coated Balloon for de novo lesions in small vessel disease (Prevail Global).

Clinical Trial

Heart and Vascular

Doctor(s) Running This Study

Shailendra Singh, MD
Location:
Lehigh Valley Hospital–Cedar Crest

NRG-GY037 Cervical Cancer

A Phase III Study of Induction Pembrolizumab and Chemotherapy Followed by Chemoradiation and Pembrolizumab vs Chemoradiation and Pembrolizumab Both Followed by Pembrolizumab for High Risk Locally Advanced Cervical Cancer

Clinical Trial

Cancer, Cervical Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

EA2222 Colorectal Cancer

A Randomized Phase III Study of Systemic Therapy With or Without Hepatic Arterial Infusion for Unresectable Colorectal Liver Metastases: The PUMP Trial

Clinical Trial

Cancer, Colorectal Cancer (Colon Cancer and Rectal Cancer)

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest

SKY-GJB2-001

A Phase 1/2, open-label, single dose study of SKY-GJB2 given as a single unilateral intracochlear administration in pediatric subjects with severe-to-profound GJB2-mediated hearing loss

Clinical Trial

Surgery, Pediatrics, Hearing Loss in Children

Phase

Phase
1

Doctor(s) Running This Study

Ravi N. Samy, MD
Location:
Lehigh Valley Hospital–Cedar Crest

TAPUR

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Clinical Trial

Cancer, Genomic

Phase

Phase
2

Doctor(s) Running This Study

Suresh G. Nair, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

Alliance A031701

ALLIANCE A031701: A PHASE II STUDY OF DOSE-DENSE GEMCITABINE PLUS CISPLATIN (DDGC) IN PATIENTS WITH MUSCLE-INVASIVE BLADDER CANCER WITH BLADDER PRESERVATION FOR THOSE PATIENTS WHOSE TUMORS HARBOR DELETERIOUS DNA DAMAGE RESPONSE (DDR) GENE ALTERATIONS

Clinical Trial

Bladder Cancer, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

Gore: Stroke (REDUCE Post Approval Study)

GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients with Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

Clinical Trial

Heart and Vascular, Neurology

Phase

Phase
4

Doctor(s) Running This Study

Paul L. Hermany, MD
Location:
Lehigh Valley Hospital–Muhlenberg

DCP-001

DCP-001, Use of a Clinical Trial Screening Tool to Address Cancer Health Disparities in the NCI Community Oncology Research Program (NCORP)

Clinical Trial

Cancer

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

A081801 Lung Cancer

INTEGRATION OF IMMUNOTHERAPY INTO ADJUVANT THERAPY FOR RESECTED NSCLC: ALCHEMIST CHEMO-IO (ACCIO)

Clinical Trial

Cancer, Lung Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

ULI-EAP-100 EXPANDED ACCESS TO ULIXERTINIB (BVD-523) IN PATIENTS WITH ADVANCED MAPK PATHWAY-ALTERED MALIGNANCIES

ULI-EAP-100 EXPANDED ACCESS TO ULIXERTINIB (BVD-523) IN PATIENTS WITH ADVANCED MAPK PATHWAY-ALTERED MALIGNANCIES

Clinical Trial

Genomic

Doctor(s) Running This Study

Suresh G. Nair, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Muhlenberg

NRG-BN011

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine®) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Clinical Trial

Cancer, Glioblastoma Multiforme (GBM)

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

Healey ALS Platform Trial

Healey ALS Platform Trial

Clinical Trial

Neurology

Phase

Phase
2

Doctor(s) Running This Study

Alison L. Walsh, MD
Location:
Lehigh Valley Hospital–Cedar Crest

A021806 Pancreatic Cancer

A Phase III Trial Of Perioperative Versus Adjuvant Chemotherapy For Resectable Pancreatic Cancer

Clinical Trial

Cancer, Pancreatic Cancer

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

AALL1732

A Phase 3 Randomized Trial of Inotuzumab Ozogamicin (IND#:133494, NSC#: 772518) for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy

Clinical Trial

Pediatric Leukemia, Pediatric Hodgkin Lymphoma

Phase

Phase
3
Location:
Lehigh Valley Hospital–Cedar Crest

AGCT1531

A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors

Clinical Trial

Pediatric Germ Cell Tumors

Phase

Phase
3
Location:
Lehigh Valley Hospital–Cedar Crest

APEC14B1

The Project: Every Child Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

Clinical Trial

Pediatric Cancer

Location:
Lehigh Valley Hospital–Cedar Crest

S1501

Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III

Clinical Trial

Breast Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Ranju Gupta, MD
Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

LungMAP

A Master Protocol to Evaluate Biomarker-Driven Therapies and Immunotherapies in Previously-Treated Non-Small Cell Lung Cancer (Lung-MAP Screening Study)

Clinical Trial

Lung Cancer, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

S1922

Randomized Phase II Selection Study of Ramucirumab and Paclitaxel versus FOLFIRI in Refractory Small Bowel Adenocarcinoma

Clinical Trial

Cancer, Gastrointestinal Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

Lung Cancer E4512: A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Placebo for Patients w/ Tumors Harboring the ALK Fusion Protein

A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib Versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

Clinical Trial

Lung Cancer, Cancer

Phase

Phase
3

Doctor(s) Running This Study

Brian J. Patson, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

A071401 Meningioma

Phase II Trial of SMO/ AKT/ NF2 Inhibitors in Progressive Meningiomas with SMO/ AKT/ NF2 Mutations

Clinical Trial

Meningioma, Cancer

Phase

Phase
2

Doctor(s) Running This Study

Suresh G. Nair, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

A022104 Rectal Cancer

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation (JANUS)

Clinical Trial

Cancer, Rectal Cancer

Phase

Phase
2

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

SWOG S1925 Lymphoma

Randomized, Phase III Study of Early Intervention with Venetoclax and Obinutuzumab Versus Delayed Therapy with Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study

Clinical Trial

Cancer, Leukemia and Lymphoma

Phase

Phase
3

Doctor(s) Running This Study

Maged F. Khalil, MD
Location:
Lehigh Valley Hospital–Cedar Crest
Lehigh Valley Hospital–Hazleton
Lehigh Valley Hospital–Muhlenberg
Lehigh Valley Hospital–Pocono

JAGUAR

Objective Analysis to Gauge EVAR Outcomes Through Randomization

Clinical Trial

Heart and Vascular

Doctor(s) Running This Study

Benjamin M. Jackson, MD, MS
Location:
Lehigh Valley Hospital–Cedar Crest

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Lehigh Valley Health Network, part of Jefferson Health, holds itself accountable, at every level of the organization, to nurture an environment of inclusion and respect, by valuing the uniqueness of every individual, celebrating and reflecting the rich diversity of its communities, and taking meaningful action to cultivate an environment of fairness, belonging & opportunity.